An analysis of gynecologic malignancies

Background A tumor marker is a substance such as a protein, antigen or hormone in the body that may indicate the presence of cancer. Generally, these markers are specific to certain types of cancer and can be detected in blood, urine and tissue samples.

An analysis of gynecologic malignancies

Abstract Objective The aims of this study were to evaluate prospectively the safety and feasibility of laparoscopic lymphadenectomy in gynecologic oncology and to analyze risk factors associated with surgical adverse events.

An analysis of gynecologic malignancies

Materials and Methods This study included consecutive laparoscopic lymphadenectomy procedures conducted in consecutive gynecologic oncology patients, between and Logistic regression analysis was used to assess the independent effects of different variables on the probability of complications.

Differences were considered to be statistically significant for P values less than 0. Results Two hundred forty-four pelvic lymphadenectomy and aortic lymphadenectomy procedures were carried out during the studied period.

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All pelvic lymphadenectomy procedures were conducted with a transperitoneal approach, whereas A total of The laparotomy conversion rate was 2.

The rate of intraoperative adverse events was 1.

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The rate of early-postoperative adverse events was 3. One patient with endometrial cancer died after surgery due to sepsis of unknown origin. The rate of late-postoperative adverse events was 3. A logistic regression analysis showed that factors associated with increased risk of lymphadenectomy surgical complications were surgical bleeding and operative time odds ratio, 2.

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Conclusions Laparoscopic lymphadenectomy is a safe and feasible procedure in gynecologic oncology but not free of complications. We postulate that gynecologic oncologists should be properly trained in the management of such complications and be aware of the importance of adequate hemostasis and operating time during surgery.Abstract Objective.

The aims of this study were to evaluate prospectively the safety and feasibility of laparoscopic lymphadenectomy in gynecologic oncology and to analyze risk factors associated with surgical adverse events. Methods. We present data from the second interim analysis of overall survival and a retrospective, preplanned analysis of data by BRCA mutation status from our randomised, double-blind, phase 2 study that assessed maintenance treatment with olaparib mg twice daily (capsules) versus placebo in patients with platinum .

High 21 patients with advanced gynecologic malignancies (13 uter- predictive value of PET-CT was thus confirmed in detecting ine tumors, and 8 ovarian cancers).

Ten patients were found relapsed ovarian cancer [24]. to be responders and 11 to be non-responders.

Gynecologic Oncology Group

Abstract. Epithelial ovarian cancer is the most common ovarian malignancy. CA, the glycoprotein defined by the antibody OC , is the most important clinical marker for the diagnosis, treatment and follow-up of epithelial ovarian cancer.

Methods. 1, patients' medical charts were reviewed who underwent therapeutic surgery for gynecologic malignancies from January 1, to December 31, . The role of pelvic exenteration and reconstruction for treatment of advanced or recurrent gynecologic malignancies: Analysis of risk factors predicting recurrence and survival.

Insights in Gynecologic Oncology- Open Access Journals